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August 4, 2010


Updated Task Force Response to NRDC Petition - August 4, 2010


The Industry Task Force II on 2,4-D Research Data ("2,4-D Task Force" or "Task Force") submits these updated comments in response to the November 6, 2008 petition of the Natural Resources Defense Council ("NRDC") requesting EPA to revoke all tolerances and cancel all registrations for the pesticide 2,4-dichlorophenoxyacetic acid ("2,4-D") (NRDC, 2008).

The 2,4-D Task Force comments have been updated to integrate results from the EPA required studies, March 2007 EPA Data Call-in. New information from the F1-extended one generation reproduction study incorporates results for reproductive toxicity, developmental neurotoxicity, developmental immunotoxicity, and endocrine end points including thyroid (Marty et al., 2010, MRID 47972101). Additionally, results are included from assays relevant to assessment of 2,4-D's potential endocrine modulating activity conducted under the auspices of the US EPA as part of the ToxCast program (Judson et al, 2009).

Download PDF: TF Updated Response to NRDC Petition